So suggests new research that tracked changes in two genes thought to help regulate brain growth, changes that appeared well after the rise of modern humans , years ago. That the defining feature of humans — our large brains — continued to evolve as recently as 5, years ago, and may be doing so today, promises to surprise the average person, if not biologists. Lahn and colleagues examined two genes, named microcephalin and ASPM, that are connected to brain size. If those genes don’t work, babies are born with severely small brains, called microcephaly. Using DNA samples from ethnically diverse populations, they identified a collection of variations in each gene that occurred with unusually high frequency. In fact, the variations were so common they couldn’t be accidental mutations but instead were probably due to natural selection, where genetic changes that are favorable to a species quickly gain a foothold and begin to spread, the researchers report. Lahn offers an analogy: Medieval monks would copy manuscripts and each copy would inevitably contain errors — accidental mutations. Years later, a ruler declares one of those copies the definitive manuscript, and a rush is on to make many copies of that version — so whatever changes from the original are in this presumed important copy become widely disseminated. Scientists attempt to date genetic changes by tracing back to such spread, using a statistical model that assumes genes have a certain mutation rate over time.
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Strait of Gibraltar The prevalent definition of Europe as a geographical term has been in use since the mid th century. Europe is taken to be bounded by large bodies of water to the north, west and south; Europe’s limits to the far east are usually taken to be the Urals, the Ural River , and the Caspian Sea ; to the southeast, including the Caucasus Mountains , the Black Sea and the waterways connecting the Black Sea to the Mediterranean Sea.
Nevertheless, there are some exceptions based on sociopolitical and cultural differences. Cyprus is closest to Anatolia or Asia Minor , but is usually considered part of Europe both culturally and politically and is a member state of the EU. Malta was considered an island of North Africa for centuries. As a name for a part of the known world, it is first used in the 6th century BC by Anaximander and Hecataeus.
The term “Europe” is first used for a cultural sphere in the Carolingian Renaissance of the 9th century. From that time, the term designated the sphere of influence of the Western Church , as opposed to both the Eastern Orthodox churches and to the Islamic world.
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Very often, foreigners come to these countries not only for the purpose of studying, business, or traveling but also with an intimate hope — that of meeting their prospective spouse.
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Nicholas Cathedral The St. Nicholas Roman Catholic Cathedral has always been regarded as the second most important Roman Catholic Cathedral in the city of Kiev, the capital of Ukraine. It was during the period of to that it was constructed in the Gothic style you see today.
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